Ketamine is a dissociative anesthetic that has been used for decades in medical settings, primarily for anesthesia and pain management.
Major depressive disorder is a severe condition that can significantly affect a person’s productivity, ability to function, and quality of life. Around 15% people face depression in their lifetime. 30% patients may not show full improvement with medication and psychotherapy. Hence there is a need for new treatment approaches to help those suffering from depression. Ketamine for depression has emerged as a promising treatment option over the last few years. The drug has been found to have antidepressant effects at low doses.
Ketamine is an anaesthetic agent which has been used safely for general anaesthesia for many decades. Recently it has been demonstrated in scientific studies that at low doses it has a rapid and robust antidepressant effect. The drug works by targeting the glutamate system in the brain, which is involved in mood regulation. It is widely gaining acceptance in the USA, Europe, and India as a treatment for people with acute depression and feeling suicidal, chronic depression or treatment-resistant depression.
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